anti- 4EBP1 antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Mouse | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Clone ID | 6C4 | | Isotype | IgG2b | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q13541 | | Calculated MW | 12 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma. | | Immunogen | eukaryotic translation initiation factor 4E binding protein 1 | | Synonyms | 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I | | Recommended dilution | WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human pancreas slide using FNab00006(4EBP1 Antibody) at dilution of 1:50
 | K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab00006 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- 4EBP1 antibody.
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