anti- Alpha-2-macroglobulin antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, IHC, WB
Delivery Time	2 to 4 working days
Clone ID	6D0
Isotype	IgG2a
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P01023
Calculated MW	163 kDa, observed 185 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
Immunogen	alpha-2-macroglobulin
Synonyms	A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, α-2M
Recommended dilution	WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:50-1:500; IHC: 1:20-1:200
Immunohistochemistry of paraffin-embedded human liver slide using FNab00341(A2M Antibody) at dilution of 1:50
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00341(A2M antibody) at dilution of 1:1000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab00341
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- Alpha-2-macroglobulin antibody. Примечание: