anti- Angiotensinogen antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Clone ID | 0F2 | | Isotype | IgG2b | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P01019 | | Gene ID | | | Calculated MW | 53 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. | | Immunogen | angiotensinogen(serpin peptidase inhibitor, clade A, member 8) | | Synonyms | AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, FLJ92595, FLJ97926, Serpin A8, SERPINA8 | | Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human liver cancer using FNab00395(AGT antibody) at dilution of 1:50
 | HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00395(AGT antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab00395 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Angiotensinogen antibody.
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