anti- APOBEC3G antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q9HC16 | | Gene ID | | | Calculated MW | 46 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | DNA deaminase(cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and-independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses(SIVs), hepatitis B virus(HBV), equine infectious anemia virus(EIAV), xenotropic MuLV-related virus(XMRV) and simian foamy virus(SFV). May inhibit the mobility of LTR and non-LTR retrotransposons. | | Immunogen | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab00495(APOBEC3G Antibody) at dilution of 1:200
 | mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab00495(APOBEC3G Antibody) at dilution of 1:100
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab00495 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- APOBEC3G antibody.
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