anti- BORIS antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human, Mouse
Tested Application	ELISA, WB, IF
Delivery Time	2 to 4 working days
Clone ID	2B10
Isotype	IgG1
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q8NI51
Calculated MW	75 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
Immunogen	CCCTC-binding factor(zinc finger protein)-like
Synonyms	BORIS, Cancer/testis antigen 27, CCCTC binding factor, CT27, CTCF like protein, CTCF paralog, CTCF T, CTCFL, dJ579F20.2, Zinc finger protein CTCF T
Recommended dilution	WB: 1:500-1:2000; IF: 1:10-1:100
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00932(BORIS antibody) at dilution of 1:1000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab00932
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- BORIS antibody. Примечание: