| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IP, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P56817 |
| Gene ID | |
| Calculated MW | 70-75 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| Immunogen | beta-site APP-cleaving enzyme 1 |
| Synonyms | BACE, KIAA1149 |
| Recommended dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400 |
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00781(BACE1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500
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