| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q7LBR1 |
| Gene ID | |
| Calculated MW | 30 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). |
| Immunogen | chromatin modifying protein 1B |
| Synonyms | C18orf2 |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded mouse kidney using FNab01657(CHMP1B antibody) at dilution of 1:50
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab01657(CHMP1B antibody) at dilution of 1:1000
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