anti- FDPS antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC, IF | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P14324 | Gene ID | | Calculated MW | 38 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | Background | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene. | Immunogen | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | Synonyms | FPS, KIAA1293 | Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 | Immunohistochemistry of paraffin-embedded rat brain using FNab03065(FDPS antibody) at dilution of 1:100
| MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03065(FDPS antibody) at dilution of 1:1000
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab03065 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- FDPS antibody. Примечание: |
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