anti- FANCD2 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse | Tested Application | ELISA, WB, IHC, IP | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q9BXW9 | Gene ID | | Calculated MW | 150-155kd | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.The antibody recognize both un-phospho and phospho-Ser(330) of FANCD2. | Immunogen | Fanconi anemia, complementation group D2 | Synonyms | DKFZp762A223, FA D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, FLJ23826, Protein FACD2 | Recommended dilution | WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human testis using FNab03006(FANCD2 antibody) at dilution of 1:50
| HL-60 cells were subjected to SDS PAGE followed by western blot with FNab03006(FANCD2 antibody) at dilution of 1:500
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab03006 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- FANCD2 antibody. Примечание: |
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