anti- c-MYC antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse | | Tested Application | ELISA, WB, IP, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P01106 | | Calculated MW | 62-65 kDa, 50 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186] | | Immunogen | v-myc myelocytomatosis viral oncogene homolog(avian) | | Synonyms | BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64 | | Recommended dilution | WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200 | Immunohistochemistry of paraffin-embedded human breast cancer using FNab01791(MYC antibody) at dilution of 1:50
 | Raji cells were subjected to SDS PAGE followed by western blot with FNab01791(MYC antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01791 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- c-MYC antibody.
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