anti- DACH1 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, IHC, IP, WB | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q9UI36 | | Gene ID | | | Calculated MW | 97-100 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter(By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain(By similarity). | | Immunogen | dachshund homolog 1(Drosophila) | | Synonyms | DACH | Immunohistochemistry of paraffin-embedded human oesophagus cancer tissue slide using FNab02230(DACH1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab02230 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- DACH1 antibody.
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