anti- HER2/ErbB2 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human
Tested Application	ELISA, WB, IHC, IF
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P04626
Gene ID
Calculated MW	185 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.
Immunogen	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog(avian)
Synonyms	CD340, ERBB2, HER 2, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1
Recommended dilution	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Immunohistochemistry of paraffin-embedded human breast cancer using FNab03834(ERBB2 antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03834(ERBB2 antibody) at dilution of 1:500

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab03834
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- HER2/ErbB2 antibody. Примечание: