anti- HLA class I(HLA-A) antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human | | Tested Application | ELISA, WB, IHC, FC | | Delivery Time | 2 to 4 working days | | Clone ID | 0D3 | | Isotype | IgG2a | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P04439/P30443 | | Gene ID | | | Calculated MW | 44 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. | | Immunogen | major histocompatibility complex, class I, A | | Synonyms | HLA A, HLA class I, HLA class I (HLA-A), HLA class I ABC, HLA-A, MHC class I antigen A*3 | | Recommended dilution | WB: 1:1000-1:8000; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab03896(HLA class I(HLA-A) Antibody) at dilution of 1:200
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab03896(HLA class I(HLA-A) Antibody) at dilution of 1:4000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab03896 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- HLA class I(HLA-A) antibody.
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