Clonality | monoclonal |
Host | Mouse |
Specificity | Human |
Tested Application | ELISA, WB,IHC |
Delivery Time | 2 to 4 working days |
Clone ID | 6A8 |
Isotype | IgG1 |
Form | liquid |
Purification | Protein A+G purification |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | P15328 |
Gene ID | |
Calculated MW | 38 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. |
Immunogen | folate receptor 1 |
Synonyms | Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1(adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha |
Recommended dilution | WB: 1:500-1:2000; IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab03185(FOLR1 Antibody) at dilution of 1:200
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03185(FOLR1 Antibody) at dilution of 1:1000
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