anti- LGR5 antibody

Clonality	polyclonal
Host	Rabbit
Specificity	Human
Tested Application	ELISA, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	O75473
Gene ID
Calculated MW	100kd
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
Immunogen	leucine-rich repeat-containing G protein-coupled receptor 5
Synonyms	FEX, G protein coupled receptor 49, G protein coupled receptor 67, GPR49, GPR67, GRP49, HG38, LGR5
Recommended dilution	IHC: 1:100-1:400
Immunohistochemical of paraffin-embedded human small intestine using FNab04765(LGR5 antibody) at dilution of 1:200

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab04765
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- LGR5 antibody. Примечание: