anti- FAM175A antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC, IF | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q6UWZ7 | Gene ID | | Calculated MW | 46 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. | Immunogen | family with sequence similarity 175, member A | Synonyms | ABRA1, CCDC98 | Immunohistochemistry of paraffin-embedded human breast cancer using FNab02974(FAM175A antibody) at dilution of 1:100
| human testis tissue were subjected to SDS PAGE followed by western blot with FNab02974(FAM175A antibody) at dilution of 1:500
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab02974 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- FAM175A antibody. Примечание: |
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