anti- MMP13 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, IHC, WB, IF | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P45452 | Gene ID | | Calculated MW | 54kd,70kd | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13(70 kDa), unglycosylated proform(54 kDa). | Immunogen | matrix metallopeptidase 13(collagenase 3) | Synonyms | CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13 | Recommended dilution | WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 | Immunohistochemistry of paraffin-embedded human breast cancer using FNab05235(MMP13 antibody) at dilution of 1:50
| MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05235(MMP13 Antibody) at dilution of 1:600
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab05235 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- MMP13 antibody. Примечание: |
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