anti- MAPKBP1 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | O60336 | Gene ID | | Calculated MW | 165 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | Background | MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. | Immunogen | mitogen-activated protein kinase binding protein 1 | Synonyms | JNKBP1, KIAA0596 | Recommended dilution | WB: 1:200 - 1:500; IHC: 1:50 - 1:100 | Immunohistochemistry of paraffin-embedded human stomach using FNab05000(MAPKBP1 antibody) at dilution of 1:100
| mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05000(MAPKBP1 antibody) at dilution of 1:300
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab05000 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- MAPKBP1 antibody. Примечание: |
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