Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse |
Tested Application | ELISA, WB |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | P20809 |
Gene ID | |
Calculated MW | 25 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production(PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation(PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. |
Immunogen | interleukin 11 |
Synonyms | Adipogenesis inhibitory factor, AGIF, IL 11, IL11, interleukin 11, Oprelvekin
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Recommended dilution | WB: 1:200-1:1000 |
human plasma tissue were subjected to SDS PAGE followed by western blot with FNab04216(IL11 Antibody) at dilution of 1:500
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