anti- PKM antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse | Tested Application | ELISA, IHC, WB | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P14618 | Gene ID | | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate(PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. | Immunogen | PKM2 pyruvate kinase, muscle | Synonyms | OIP3, PK2, PK3, PKM2 | Immunohistochemistry of paraffin-embedded human colon cancer using FNab06492(PKM antibody) at dilution of 1:50
| | |
Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab06493 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- PKM antibody. Примечание: |
|