anti- MUC1 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human
Tested Application	ELISA, WB, FC, IHC, IP
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P15941
Calculated MW	122 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Immunogen	mucin 1, cell surface associated
Synonyms	CA15 3, CA153, CA15-3, Carcinoma associated mucin, CD227, EMA, Episialin, H23AG, KL-6, MAM6, MUC 1, MUC1, MUC1 beta, MUC1 CT, MUC1 NT, Mucin 1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated mucin
Recommended dilution	WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Immunohistochemistry of paraffin-embedded human lung cancer using FNab05427(CA15-3,MUC1 antibody) at dilution of 1:50
A431 cells were subjected to SDS PAGE followed by western blot with FNab05427(CA15-3,MUC1 antibody) at dilution of 1:1500

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab05427
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- MUC1 antibody. Примечание: