anti- PSMC3 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC, IF | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P17980 | Gene ID | | Calculated MW | 49 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. | Immunogen | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | Synonyms | TBP1 | Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 | Immunohistochemistry of paraffin-embedded rat liver using FNab06879( PSMC3 Antibody) at dilution of 1:50
![](https://www.fn-test.com/content/uploads/product/images/antibody/image1/FNab06879.jpg) | HeLa cells were subjected to SDS PAGE followed by western blot with FNab06879(PSMC3 antibody) at dilution of 1:1000
![](https://www.fn-test.com/content/uploads/product/images/antibody/image4/FNab06879.jpg) | | |
Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab06879 | Цена (с НДС 20%): | по запросу | В корзину ![](/catalog/cart.gif) | Наименование: anti- PSMC3 antibody. Примечание: |
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