Clonality | polyclonal |
Host | Rabbit |
Specificity | Human |
Tested Application | ELISA, WB, IHC, IF, IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q16576 |
Gene ID | |
Calculated MW | 48 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Background | This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | retinoblastoma binding protein 7 |
Synonyms | Histone binding protein RBBP7, RbAp46, RBBP 7, RBBP7 |
Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200 |
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab07147(RBBP7 antibody) at dilution of 1:50
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A431 cells were subjected to SDS PAGE followed by western blot with FNab07147(RBBP7 antibody) at dilution of 1:1000
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