Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, WB |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q8TBB1 |
Gene ID | |
Calculated MW | 70 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity).
Isoform 2 provides an endocytic scaffold for IGSF5/JAM4. |
Immunogen | ligand of numb-protein X 1 |
Synonyms | LNX, PDZRN2 |
Recommended dilution |
WB: 1:500-1:2000 |
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab04814(LNX1 antibody) at dilution of 1:100
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