Clonality | polyclonal |
Host | Rabbit |
Specificity | Human |
Tested Application | ELISA, WB, IHC, IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q96RN5 |
Gene ID | |
Calculated MW | 105 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. |
Immunogen | mediator complex subunit 15 |
Synonyms | ARC105, CTG7A, PCQAP, TIG1, TNRC7 |
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab05089(MED15 antibody) at dilution of 1:100
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