| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC, IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P31483 |
| Gene ID | |
| Calculated MW | 54 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. |
| Immunogen | TIA1 cytotoxic granule-associated RNA binding protein |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100 |
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08685(TIA1 antibody) at dilution of 1:100
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BT-474 cells were subjected to SDS PAGE followed by western blot with FNab08685(TIA1 antibody) at dilution of 1:1000
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