| Highlight | Pubmed/Publication |
| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse |
| Tested Application | ELISA, WB, IP, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P08183 |
| Calculated MW | 142KD |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. |
| Immunogen | ABCB1 |
| Synonyms | ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1 |
| Recommended dilution | WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09805(P glycoprotein antibody) at dilution of 1:500
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09805(P glycoprotein antibody) at dilution of 1:300
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