Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat, Zebrafish |
Tested Application | ELISA, WB, IF |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q96D31 |
Gene ID | |
Calculated MW | 45 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901). |
Immunogen | ORAI calcium release-activated calcium modulator 1 |
Synonyms | CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A |
Recommended dilution | WB: 1:500-1:1000; IF: 1:10-1:100 |
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06001(ORAI1 antibody) at dilution of 1:800
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