| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC, IF, IP |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P08235 |
| Gene ID | |
| Calculated MW | 107 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Receptor for both mineralocorticoids(MC) such as aldosterone and glucocorticoids(GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements(MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. |
| Immunogen | nuclear receptor subfamily 3, group C, member 2 |
| Synonyms | MCR, Mineralocorticoid receptor, MLR, MR, NR3C2 |
| Recommended dilution | WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:10-1:100 |
Immunohistochemistry of paraffin-embedded human kidney using FNab05846(NR3C2 antibody) at dilution of 1:50
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05846(NR3C2 antibody) at dilution of 1:1000
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