anti- P16-INK4A antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IF, IP, IHC, FC | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P42771 | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma. | Immunogen | cyclin-dependent kinase inhibitor 2A(melanoma, p16, inhibits CDK4) | Synonyms | ARF,CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, p14, p14ARF, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, P19, TP16 | Recommended dilution | WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab06064(P16-INK4A Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
| HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06064(P16 antibody) at dilution of 1:1000
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab06064 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- P16-INK4A antibody. Примечание: |
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