anti- Vimentin antibodyСпецификацияClonality | monoclonal | Host | Mouse | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC | Delivery Time | 2 to 4 working days | Clone ID | 2G10 | Isotype | IgG1 | Form | liquid | Purification | Protein A+G purification | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P08670 | Calculated MW | 55 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level. | Immunogen | vimentin | Synonyms | FLJ36605, VIM, Vimentin | Recommended dilution | WB: 1:1000-1:10000; IHC: 1:20-1:2000; IF: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab09410(Vimentin Antibody) at dilution of 1:500.
| Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09410(Vimentin Antibody) at dilution of 1:2000
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab09410 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- Vimentin antibody. Примечание: |
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