anti- UBR2 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse | | Tested Application | ELISA, WB, IF, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q8IWV8 | | Gene ID | | | Calculated MW | 53 kDa, Observed 70 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. | | Immunogen | ubiquitin protein ligase E3 component n-recognin 2 | | Synonyms | BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2 | | Recommended dilution | WB: 1:200-1:2000; IF：1：10-1:100; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab09209(UBR2 Antibody) at dilution of 1:50
 | BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab09209(UBR2 antibody) at dilution of 1:600
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09209 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- UBR2 antibody.
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