anti- Phospho-VEGF Receptor 2-Y1175 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P35968 | Gene ID | | Calculated MW | 250 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas. | Immunogen | A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2 | Synonyms | CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2 | Recommended dilution | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 | Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using FNab09964 at dilution of 1:50
| HUVE cells were subjected to SDS PAGE followed by western blot with FNab09964 at dilution of 1:600
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab09964 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- Phospho-VEGF Receptor 2-Y1175 antibody. Примечание: |
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