anti- PIK3C2A antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | O00443 | | Gene ID | | | Calculated MW | 191 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | | Background | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. | | Immunogen | phosphoinositide-3-kinase, class 2, alpha polypeptide | | Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:100 - 1:200 | Immunohistochemistry of paraffin-embedded rat heart using FNab06449(PIK3C2A antibody) at dilution of 1:100
 | PC-3 cells were subjected to SDS PAGE followed by western blot with FNab06449(PIK3C2A antibody) at dilution of 1:1500
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab06449 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- PIK3C2A antibody.
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