Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse |
Tested Application | ELISA, WB, IHC, IF |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q14764 |
Gene ID | |
Calculated MW | 100 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Background | This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. |
Immunogen | major vault protein |
Synonyms | LRP, major vault protein, MVP, VAULT1 |
Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05449( MVP Antibody) at dilution of 1:200
![](https://www.fn-test.com/content/uploads/product/images/antibody/image1/FNab05449.jpg) |
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab05449(MVP antibody) at dilution of 1:1000
![](https://www.fn-test.com/content/uploads/product/images/antibody/image4/FNab05449.jpg) |
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