Clonality | polyclonal |
Host | Rabbit |
Specificity | Human |
Tested Application | ELISA, WB, IHC, IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q6IQ22 |
Gene ID | |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy(By similarity). |
Immunogen | RAB12, member RAS oncogene family |
Immunohistochemistry of paraffin-embedded human liver using FNab06995(RAB12 antibody) at dilution of 1:100
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab06995(RAB12 antibody) at dilution of 1:500
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