Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, WB, IP,IHC |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | P19532 |
Gene ID | |
Calculated MW | 65KD |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
Immunogen | transcription factor binding to IGHM enhancer 3 |
Synonyms | bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3 |
Recommended dilution | WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab08626(TFE3 Antibody) at dilution of 1:200
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K-562 cells were subjected to SDS PAGE followed by western blot with FNab08626(TFE3 antibody) at dilution of 1:1000
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