anti- SH2D1A antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	O60880
Gene ID
Calculated MW	17 kDa
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Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen	SH2 domain protein 1A
Synonyms	DSHP, SAP
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human liver cancer using FNab07819(SH2D1A antibody) at dilution of 1:100
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07819(SH2D1A antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab07819
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- SH2D1A antibody. Примечание: