anti- ZFP36L2 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P47974
Gene ID
Calculated MW	51 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity).
Immunogen	zinc finger protein 36, C3H type-like 2
Synonyms	BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2
Recommended dilution	WB: 1:200-1:2000
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09625(ZFP36L2 antibody) at dilution of 1:500

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09625
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- ZFP36L2 antibody. Примечание: