anti- RBPJ antibody

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, WB
Delivery Time	2 to 4 working days
Clone ID	2A10
Isotype	IgG1
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q06330
Gene ID
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins(Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions(4% oxygen)(PubMed:23303788).
Immunogen	recombination signal binding protein for immunoglobulin kappa J region
Synonyms	IGKJRB, IGKJRB1, RBPJK, RBPSUH
WB Image

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab07196
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- RBPJ antibody. Примечание: