Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse |
Tested Application | ELISA, WB, IHC, IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | O43293 |
Calculated MW | 53 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | DAPK3(Death-associated protein kinase 3) is also named as ZIPK(Zipper-interacting protein kinase),Dlk(DAP-like kinase). It is a member of the death-associated protein kinase family associated with apoptosis in nonmuscle cells where it phosphorylates myosin regulatory light chain(RLC) to promote membrane blebbing. DAPK3 mRNA and protein are abundant in heart tissue and isolated ventricular neonatal rat cardiac myocytes(PMID:20038585). It has 2 isoforms produced by alternative splicing,named as ZIPK-L and ZIPK-S. This antibody is specific to ZIPK-Phospho 311Ser. |
Immunogen | death-associated protein kinase 3 |
Synonyms | DAP kinase 3, DAP like kinase, DAPK3, Dlk, FLJ36473, ZIP, ZIP kinase, ZIPK |
Recommended dilution | WB: 1:500-1:5000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09644(ZIPK-Phospho 311Ser antibody) at dilution of 1:50
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09644(ZIPK-Phospho 311Ser antibody) at dilution of 1:1000
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