| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P09874 |
| Gene ID | |
| Calculated MW | 115 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
| Immunogen | poly (ADP-ribose) polymerase 1 |
| Synonyms | ADPRT, PPOL |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06151(PARP1 antibody) at dilution of 1:100
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab06151(PARP1 Antibody) at dilution of 1:1000
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