Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat, Zebrafish |
Tested Application | ELISA, IF, WB, IHC |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | P48431 |
Gene ID | |
Calculated MW | 34kd |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity). |
Immunogen | SRY(sex determining region Y)-box 2 |
Synonyms | ANOP3, MCOPS3, SOX2, Transcription factor SOX 2 |
Recommended dilution | WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human lung cancer tissue using FNab08125(SOX2 Antibody) at dilution of 1:100
![](https://www.fn-test.com/content/uploads/product/images/antibody/image1/FNab08125.jpg) |
U-251 cells were subjected to SDS PAGE followed by western blot with FNab08125(SOX2 antibody) at dilution of 1:5000
![](https://www.fn-test.com/content/uploads/product/images/antibody/image4/FNab08125.jpg) |
| |