anti- STK24 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q9Y6E0 | Gene ID | | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2(MAPK8 and MAPK9), p38(MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve. | Immunogen | serine/threonine kinase 24(STE20 homolog, yeast) | Synonyms | MST3, STK3 | | |
Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab08327 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- STK24 antibody. Примечание: |
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