Anti- VEGF antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, WB, IHC
Delivery Time	2 to 4 working days
Clone ID	5H5
Isotype	IgG2b
Form	liquid
Purification	protein A+G purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P15692
Calculated MW	45 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	0.01MPBS pH 7.4,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA.
Immunogen	vascular endothelial growth factor A
Synonyms	L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF
Recommended dilution	WB: 1:1000-1:4000; IHC: 1:50-1:500
Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab09933 (VEGF antibody) at dilution of 1:200
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab09933 (VEGF antibody) at dilution of 1:2000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09933
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Anti- VEGF antibody. Примечание: