anti- VWF, VWFpp antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P04275
Calculated MW	82 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Von Willebrand factor(vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII(FVIII). Deficiency of vWF results in von Willebrand disease(vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids(aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide(vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region(residues 56-256 aa) of pre-pro-vWF recognizes von Willebrand antigen 2(75-83 kDa) and pro-vWF(309-320 kDa).(PMID: 9759493; 12067899; 22452980; 8874191)
Immunogen	von Willebrand factor
Synonyms	F8VWF, von Willebrand antigen II, von Willebrand factor, VWD, VWF
Recommended dilution	WB: 1:200-1:2000；IHC: 1:100-1:400
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab09466(VWF, VWFpp Antibody) at dilution of 1:200
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09466(VWF, VWFpp antibody) at dilution of 1:500

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09466
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- VWF, VWFpp antibody. Примечание: