anti- WWP1 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IP | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q9H0M0 | Gene ID | | Calculated MW | 47 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF. | Immunogen | WW domain containing E3 ubiquitin protein ligase 1 | Synonyms | AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1 | Recommended dilution | WB: 1:200-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 | PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09534(WWP1 antibody) at dilution of 1:300
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab09534 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- WWP1 antibody. Примечание: |
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