Highlight | Pubmed/Publication |
Clonality | monoclonal |
Host | Mouse |
Specificity | Human |
Tested Application | ELISA, WB, IHC |
Delivery Time | 2 to 4 working days |
Clone ID | 8F7 |
Isotype | IgG1 |
Form | liquid |
Purification | Protein A+G purification |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | O94782 |
Gene ID | |
Calculated MW | 88 kDa, Observed 88 kDa,100 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029). |
Immunogen | ubiquitin specific peptidase 1 |
Synonyms | Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1 |
Recommended dilution | WB: 1:1000-1:10000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09303(USP1 antibody) at dilution of 1:50
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09303(USP1 Antibody) at dilution of 1:2000
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