Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse |
Tested Application | ELISA, WB, IF |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q9BRR0 |
Gene ID | |
Calculated MW | 62 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
Immunogen | zinc finger with KRAB and SCAN domains 3 |
Synonyms | ZKSCAN3, dJ874C20.1, KIAA0426, ZF47, ZFP306 |
Recommended dilution | WB: 1:500-1:5000; IF: 1:10-1:100 |
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09646(ZKSCAN3 antibody) at dilution of 1:500
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