anti- UBE3A antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q05086
Gene ID
Calculated MW	110 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.
Immunogen	ubiquitin protein ligase E3A
Synonyms	ANCR, AS, E6 AP, E6AP, E6AP ubiquitin protein ligase, EPVE6AP, FLJ26981, HPVE6A, UBE3A, ubiquitin protein ligase E3A
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human kidney using FNab09189(UBE3A antibody) at dilution of 1:100
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09189(UBE3A antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09189
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- UBE3A antibody. Примечание: